Which term refers to changes in allele frequencies due to random sampling?

The term that refers to changes in allele frequencies due to random sampling is genetic drift. Genetic drift is a mechanism of evolution that occurs when there are random changes in the allele frequencies within a population from one generation to the next. This can happen in small populations where the reproductive success of individuals can significantly affect the population's allele frequencies purely by chance. As a result, certain alleles may become more or less common over generations, leading to a loss of genetic variation and potentially impacting the evolution of the population.

In contrast, artificial selection involves human intervention in breeding practices to enhance desired traits. The Krebs cycle is a crucial metabolic pathway for energy production in cells and is not related to genetic variation. Coevolution refers to the evolutionary changes that occur in two or more species that interact with one another, affecting their evolutionary paths, which is distinct from the random changes in allele frequencies seen in genetic drift.